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대한소화기내시경학회> Clinical Endoscopy

Clinical Endoscopy update

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  • : 대한소화기내시경학회지(~2011)→Clinical Endoscopy(2012~)

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수록범위 : 44권1호(2011)~54권1호(2021) |수록논문 수 : 1,067
Clinical Endoscopy
54권1호(2021년 01월) 수록논문
최근 권호 논문
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KCI등재 SCOPUS

1Giant Rugae in Helicobacter pylori-Infected Stomachs

저자 : Sun-young Lee

발행기관 : 대한소화기내시경학회 간행물 : Clinical Endoscopy 54권 1호 발행 연도 : 2021 페이지 : pp. 1-3 (3 pages)

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2Colon Capsule Endoscopy: An Alternative for Conventional Colonoscopy?

저자 : Britt B. S. L. Houwen , Evelien Dekker

발행기관 : 대한소화기내시경학회 간행물 : Clinical Endoscopy 54권 1호 발행 연도 : 2021 페이지 : pp. 4-6 (3 pages)

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3Is Carcinoembryonic Antigen the Holy Grail for Pancreatic Cyst Risk Stratification?

저자 : Ahmad Najdat Bazarbashi , Linda S. Lee

발행기관 : 대한소화기내시경학회 간행물 : Clinical Endoscopy 54권 1호 발행 연도 : 2021 페이지 : pp. 7-8 (2 pages)

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4The Clinical and Metabolic Effects of Intragastric Balloon on Morbid Obesity and Its Related Comorbidities

저자 : Joon Hyun Cho , Mohammad Bilal , Min Cheol Kim , Jonah Cohen

발행기관 : 대한소화기내시경학회 간행물 : Clinical Endoscopy 54권 1호 발행 연도 : 2021 페이지 : pp. 9-16 (8 pages)

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Obesity is becoming increasingly prevalent worldwide, and its metabolic sequelae lead to a significant burden on healthcare resources. Options for the management of obesity include lifestyle modification, pharmacological treatment, surgery, and endoscopic bariatric therapies (EBTs). Among these, EBTs are more effective than diet and lifestyle modification and are less invasive than bariatric surgery. In recent years, there have been significant advances in technologies pertaining to EBTs. Of all the available EBTs, there is a significant amount of clinical experience and published data regarding intragastric balloons (IGBs) because of their comparatively long development period. Currently, the United States Food and Drug Administration (FDA) has approved three IGBs, including Orbera (Apollo Endosurgery, Austin, TX, USA), ReShape Duo (ReShape Medical, San Clemente, CA, USA), and Obalon (Obalon Therapeutics, Carlsbad, CA, USA). The aim of this review is to summarize the available literature on the efficacy of IGBs in weight loss and their impact on obesity-related metabolic diseases. Clin Endosc 2021;54:9-16

KCI등재 SCOPUS

5The Efficacy and Safety of Endoscopic Sleeve Gastroplasty as an Alternative to Laparoscopic Sleeve Gastrectomy

저자 : Jin Young Yoon , Román Turró Arau

발행기관 : 대한소화기내시경학회 간행물 : Clinical Endoscopy 54권 1호 발행 연도 : 2021 페이지 : pp. 17-24 (8 pages)

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Endoscopic sleeve gastroplasty (ESG) is a therapeutic endoscopic technique for reducing the size of the gastric reservoir in obese patients, using a full-thickness endoscopic suturing device. The effectiveness of ESG in weight loss is significantly greater than that of high-intensity diet and lifestyle therapy and lower than that of laparoscopic sleeve gastrectomy (LSG). The efficacy at 12 months after ESG in terms of percentage of total body weight loss and excess body weight loss was approximately 16% and 60%, respectively. The well-known predictive factors for increased weight loss by ESG are good compliance with regular monitoring and post-procedure care involving a multidisciplinary team approach. Although the underlying mechanism of weight loss induced by ESG is debatable, delayed gastric emptying and early satiation are some of the proposed mechanisms. The pooled rate of adverse events after ESG reported in several meta-analysis studies ranged from 1.5% to 2.3% and the incidence of new-onset gastroesophageal reflux disease after ESG was negligible, indicating that ESG has a superior safety profile to LSG. Moreover, ESG reduced the risk of obesity-related metabolic comorbidities, evidenced by the reduction in HbA1c level, systolic blood pressure, triglyceride level, and risk of hepatic steatosis and fibrosis; it even improved the quality of life. ESG could be considered safe and qualify as an alternative treatment to LSG. Clin Endosc 2021;54:17-24

KCI등재 SCOPUS

6Various Novel and Emerging Technologies in Endoscopic Bariatric and Metabolic Treatments

저자 : Hee Kyong Na , Diogo Turiani Hourneaux De Moura

발행기관 : 대한소화기내시경학회 간행물 : Clinical Endoscopy 54권 1호 발행 연도 : 2021 페이지 : pp. 25-31 (7 pages)

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Obesity, along with its comorbidities, has become a significant public health concern worldwide. Bariatric surgery is considered the most effective treatment modality; however, only 2% of patients with obesity undergo bariatric surgery. Endoscopic bariatric and metabolic therapies (EBMTs) are emerging alternatives to traditional bariatric surgery for patients who are not eligible for or do not prefer surgical treatment. EBMTs are generally categorized as space-occupying, gastric restrictive, aspiration, and small bowel therapies. We aimed to review various non-balloon and non-gastroplasty devices with available clinical data and discuss the possible mechanisms of action, efficacy, and safety profile of these EMBTs. Clin Endosc 2021;54:25-31

KCI등재 SCOPUS

7Trends of Colorectal Cancer Prevalence in Kazakhstan Related to Screening

저자 : Alma Zhylkaidarova , Dilyara Kaidarova , Kanat Batyrbekov , Oxana Shatkovskaya , Dinara Begimbetova

발행기관 : 대한소화기내시경학회 간행물 : Clinical Endoscopy 54권 1호 발행 연도 : 2021 페이지 : pp. 32-37 (6 pages)

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We carried out an analysis of the total incidence of colon cancer throughout Kazakhstan. Retrospectively, according to the regional reports on endoscopic screening, the study showed an increase in the age-related incidence of colorectal cancer (CRC) cases from 2004-2008 to 2009-2014. The peak of morbidity in both periods was noted in the age category of >70 years. The indicators of the territorial distribution of CRC incidence make it possible to divide the regions into areas with low or high rates of CRC. Specific indicators showed newly diagnosed cases of CRC stages I, II, III, and IV in 2004-2018. The incidence rates of stages I and II showed a two-fold increase (35%-67.4%) and the incidence of stage IV showed a decline from 19.3% to 13.1% and of stage III from 45.7% to 19.5% from 2004 to 2018, respectively. An analysis of CRC incidence throughout Kazakhstan showed an increase in the overall incidence. Since population-based CRC screening was introduced in 2011, the morbidity was found to increase for stages I and II. Clin Endosc 2021;54:32-37

KCI등재 SCOPUS

8The Role of Needle-Based Confocal Laser Endomicroscopy in the Evaluation of Pancreatic Cystic Lesions: A Systematic Review

저자 : Yung Ka Chin , Clement Chun Ho Wu , Damien Meng Yew Tan

발행기관 : 대한소화기내시경학회 간행물 : Clinical Endoscopy 54권 1호 발행 연도 : 2021 페이지 : pp. 38-47 (10 pages)

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The prevalence of pancreatic cystic lesions (PCLs) has increased recently due to the increased use of cross-sectional abdominal imaging and the ageing global population. Current diagnostic techniques are inadequate to distinguish between PCLs that require surgery, close surveillance, or expectant management. This has resulted in increased morbidity from both inappropriately aggressive and conservative management strategies. Needle-based confocal laser endomicroscopy (nCLE) has allowed microscopic examination and visual delineation of the surface epithelium of PCLs. Landmark studies in this decade have correlated nCLE and histological findings and identified characteristics differentiating various types of PCLs. Subsequent studies have confirmed the high diagnostic yield of nCLE and its diagnostic utility in PCLs with an equivocal diagnosis. Moreover, nCLE has been shown to improve the diagnostic yield of PCLs. This will help avoid unnecessary pancreatic surgery, which carries significant morbidity and mortality risks. The early detection of high-grade dysplasia in PCLs will provide early surgical treatment and improve outcomes for pancreatic cancer. Despite the high upfront cost of nCLE, the improved diagnostic accuracy and resultant appropriate management have resulted in improved cost effectiveness. Refining the procedure technique and limiting the procedure length have significantly improved the safety of nCLE. A structured training program and device improvements to allow more complete mapping of the pancreatic cyst epithelium will be crucial for the widespread adoption of this promising technology. Clin Endosc 2021;54:38-47

KCI등재 SCOPUS

9Changes in Policy and Endoscopic Procedures during the 2019 Coronavirus Disease Outbreak: A Single Center Experience

저자 : Adi Lahat , Avidan Benjamin

발행기관 : 대한소화기내시경학회 간행물 : Clinical Endoscopy 54권 1호 발행 연도 : 2021 페이지 : pp. 48-54 (7 pages)

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Background/Aims: The coronavirus disease-19 (COVID-19) pandemic forced endoscopy units to enact major changes on daily practice and policy. The Chaim Sheba Medical Center is a tertiary referral center located in the center of Israel, and serves cities with high infection rates. Our aim was to review the policies enacted during this outbreak and study their influence on the performance of endoscopic procedures.
Methods: Following the revision of work protocols, personnel were divided into two permanent and physically separate working groups and screening procedures were rescheduled. Relevant data including the number of endoscopic examinations, type of procedure performed, and patient referrals and indications were taken from a computerized database and evaluated. The study included data for January-March 2018-2020, and a comparison among the data from each year was performed.
Results: As of March 2020, the total number of endoscopic examinations performed reduced by 44% (p<0.0001) as compared to previous years, gastroscopy examinations reduced by 39% (p=0.02), and lower endoscopy procedures reduced by 57% (p<0.0001). Meanwhile, the number of advanced endoscopic procedures performed remained consistent with previous years. The indications for performance of gastroscopy and lower endoscopy were different in March 2020, while these remained unchanged for advanced endoscopic procedures.
Conclusions: The current policy appears to serve both our initial goals: protecting personnel and patients' safety and minimizing potential damage from delayed endoscopic procedures. A longer term follow-up study is needed in order to fully analyze our results. Clin Endosc 2021;54:48-54

KCI등재 SCOPUS

10Confocal Laser Endomicroscopic Findings of Refractory Erosive Reflux Disease versus Non-Erosive Reflux Disease with Anti-Reflux Mucosectomy: An in vivo and ex vivo Study

저자 : Eunju Jeong , In Kyung Yoo , Abdullah Özgür Yeniova , Dong Keon Yon , Joo Young Cho

발행기관 : 대한소화기내시경학회 간행물 : Clinical Endoscopy 54권 1호 발행 연도 : 2021 페이지 : pp. 55-63 (9 pages)

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Background/Aims: To date, there is no standard tool to diagnose gastroesophageal reflux disease (GERD). Typically, GERD is a non-erosive reflux disease (NERD) that does not present endoscopic abnormalities. Confocal laser endomicroscopy (CLE) has been shown to be an effective tool to identify and diagnose GERD. We aimed to investigate the cellular and vascular changes in vivo and ex vivo through CLE in patients with GERD.
Methods: Patients with refractory GERD who underwent mucosectomy were recruited. The distal esophagus was observed in vivo using CLE. Mucosectomy tissue was stained with acriflavine and CLE image was obtained ex vivo. We compared cellular and vascular changes in CLE between erosive reflux disease (ERD), NERD, and a control group.
Results: Eleven patients who underwent anti-reflux mucosectomy and five control patients were enrolled in the study. Patients with ERD and NERD presented greater dilated intercellular space than patients in the control group on CLE image. The diameter, number, and cross-sectional area of the intra-papillary capillary loops (IPCLs) were significantly larger in the ERD group than in the NERD group. The irregular shape of the IPCLs were observed in both patients with ERD and NERD.
Conclusions: The irregular shape of the IPCLs were significantly correlated with a positive diagnosis of GERD. CLE may diagnose NERD with high sensitivity and accuracy. Clin Endosc 2021;54:55-63

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